Publications @ University of Vienna
Guarrochena X, Kanellopoulos P, Stingeder A, Rečnik LM, Feiner IVJ, Brandt M et al. Amide-to-Triazole Switch in Somatostatin-14-Based Radioligands: Impact on Receptor Affinity and In Vivo Stability. Pharmaceutics. 2024 Mar;16(3):392. doi: 10.3390/pharmaceutics16030392
Guarrochena X, Kronberger J, Tieber M, Ciesielski P, Mindt TL, Feiner IVJ. Straightforward Synthesis of DFO* - An Octadentate Chelator for Zirconium-89. ChemMedChem. 2024 Feb 1;19(3):e202300495. doi: 10.1002/cmdc.202300495
Guarrochena X, Anderla M, Salomon P, Feiner IVJ, Nock BA, Maina T et al. Combination of the amide-to-triazole substitution strategy with alternative structural modifications for the metabolic stabilization of tumor-targeting, radiolabeled peptides. Journal of Peptide Science. 2024. doi: 10.1002/psc.3654
Happl B, Balber T, Heffeter P, Denk C, Welch JM, Köster U et al. Synthesis and preclinical evaluation of BOLD-100 radiolabeled with ruthenium-97 and ruthenium-103. Dalton Transactions. 2024. Epub 2024. doi: 10.1039/d4dt00118d
Schmitl S, Raitanen J, Witoszynskyj S, Patronas EM, Nics L, Ozenil M et al. Quality Assurance Investigations and Impurity Characterization during Upscaling of [177Lu]Lu-PSMAI&T. Molecules. 2023 Dec;28(23):7696. doi: 10.3390/molecules28237696
Happl B, Brandt M, Balber T, Benčurová K, Talip Z, Voegele A et al. Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100. Pharmaceutics. 2023 Nov;15(11):2626. doi: 10.3390/pharmaceutics15112626
Wang Y, Felder PS, Mesdom P, Blacque O, Mindt TL, Cariou K et al. Towards Ruthenium(II)-Rhenium(I) Binuclear Complexes as Photosensitizers for Photodynamic Therapy. ChemBioChem. 2023 Oct 4;24(19):e202300467. doi: 10.1002/cbic.202300467
Guarrochena X, Kaudela B, Mindt TL. Automated solid-phase synthesis of metabolically stabilized triazolo-peptidomimetics. Journal of Peptide Science. 2023 Sep;29(9):e3488. doi: 10.1002/psc.3488
Wang Y, Staudinger JN, Mindt TL, Gasser G. Theranostics with photodynamic therapy for personalized medicine: to see and to treat. Theranostics. 2023;13(15):5501-5544. doi: 10.7150/thno.87363
Jouini N, Cardinale J, Mindt TL. Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD-L1. ChemMedChem. 2022 Jun 20;17(12):e202200091. Epub 2022 Apr 28. doi: 10.1002/cmdc.202200091
Rischka L, Vraka C, Pichler V, Rasul S, Nics L, Gryglewski G et al. First-in-Humans Brain PET Imaging of the GluN2B-Containing N-methyl-D-aspartate Receptor with (R)-C-11-Me-NB1. Journal of Nuclear Medicine. 2022 Jun 1;63(6):936-941. doi: 10.2967/jnumed.121.262427
Giammei C, Jouini N, Brandt MR, Frey S, Mindt TL, Cardinale J. Unexpected transformation of n.c.a. [
111In]InCl
3 in stock solutions into an unreactive [
111In]In-species. Applied Radiation and Isotopes. 2022 Feb;180:110037. doi: 10.1016/j.apradiso.2021.110037
Rischka L, Murgaš M, Pichler V, Vraka C, Rausch I, Winkler D et al. Biodistribution and dosimetry of the GluN2B-specific NMDA receptor PET radioligand (R)-[11C]Me-NB1. EJNMMI Research. 2022;12(1):53. doi: 10.1186/s13550-022-00925-8
Klasen B, Lemcke D, Mindt TL, Gasser G, Roesch F. Development and in vitro evaluation of new bifunctional
89Zr-chelators based on the 6-amino-1,4-diazepane scaffold for immuno-PET applications. Nuclear Medicine and Biology. 2021 Nov 1;102-103:12-23. doi: 10.1016/j.nucmedbio.2021.06.007
Feiner IVJ, Brandt M, Cowell J, Demuth T, Vugts D, Gasser G et al. The Race for Hydroxamate-Based Zirconium-89 Chelators. Cancers. 2021 Sep;13(17):4466. doi: 10.3390/cancers13174466
Grob NM, Schibli R, Behe M, Mindt TL. Improved Tumor-Targeting with Peptidomimetic Analogs of Minigastrin Lu-177-PP-F11N. Cancers. 2021 Jun;13(11):2629. doi: 10.3390/cancers13112629
Grob NM, Schibli R, Behe M, Valverde IE, Mindt TL. 1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs. ACS Medicinal Chemistry Letters . 2021 Apr 8;12(4):585-592. doi: 10.1021/acsmedchemlett.0c00636
Vrettos E, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M et al. Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity. Chemistry: A European Journal. 2020 Aug 21;26(47):10690-10694. doi: 10.1002/chem.202000924
Recnik L-M, Kandioller W, Mindt TL. 1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity. Molecules. 2020 Aug;25(16):3576. doi: 10.3390/molecules25163576
Brandt M, Cowell J, Aulsebrook ML, Gasser G, Mindt TL. Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68. Journal of Biological Inorganic Chemistry. 2020 Jul 13;25:789-796. doi: 10.1007/s00775-020-01800-4